Laboratory of Analytical Chemistry for Pharmaceutical Sciences

学術論文（2015年度）

1. Yamamoto S, Nagai E, Asada Y, Kinoshita M Suzuki S., A rapid and highly sensitive microchip electrophoresis of mono- and mucin-type oligosaccharides labeled with 7-amino-4-methylcoumarin Anal. Bioanal. Chem. (2015) in press

学術論文（2014年度）

1. Iwatsuka K, Iwamoto H, Kinoshita M, Inada K, Yasueda S, Kakehi K., Comparative Studies of N-Glycans and Glycosaminoglycans Present in SIRC (Statens Seruminstitut Rabbit Cornea) Cells and Corneal Epithelial Cells from Rabbit Eyes. Curr Eye Res. 39 (2014) 686-694

2. Kinoshita M, Mitsui Y, Kakoi N, Yamada K, Hayakawa T, Kakehi K., Common glycoproteins expressing polylactosamine-type glycans on matched patient primary and metastatic melanoma cells show different glycan profiles, J Proteome Res. 13(2) (2014) 1021-1033

3. Suzuki S., Highly Sensitive Methods Using Liquid Chromatography and Capillary Electrophoresis for Quantitative Analysis of Glycoprotein Glycans different glycan profiles, Chromatography 35 (2014) 1-22

4. Yagi Y, Kakehi K, Hayakawa T, Suzuki S., Application of Microchip Electrophoresis Sodium Dodecyl Sulfate for the Evaluation of Change of Degradation Species of Therapeutic Antibodies in Stability Testing, Anal. Sci. 30 (2014) 483-488 DOI:http://dx.doi.org/10.2116/analsci.30.483

学術論文（2013年度）

1. Yodoshi M, Ikeda N, Yamaguchi N, Nagata M, Nishida N, Kakehi K, Hayakawa T, Suzuki S., A novel condition for capillary electrophoretic analysis of reductively aminated saccharides without removal of excess reagents, Electrophoresis, 34 (2013) 3198-3205 DOI: 10.1002/elps.201200612

2. Yamamoto S, Nakatani Y, Suzuki S., Application of online preconcentration affinity capillary electrophoresis method to glycans labeled with 8-aminopyrene-1,3,6-trisulfonic acid using blue light emittting diode-induced fluorescence detection, Anal. Sci., 29 (2013) 831-835 DOI: http://dx.doi.org/10.2116/analsci.29.831

3. Yagi Y, and Suzuki S, Focusing Review - Characterization of oligosaccharides in therapeutic antibodies, Chromatography, 34 (2013) 83-88

4. Kinoshita M, Nakatsuji Y, Suzuki S, Hayakawa T, Kakehi K., Quality Assurance of Monoclonal Antibody Pharmaceuticals Based on Their Charge Variants Using Microchip Isoelectric Focusing Method, J. Chromatogr. A, 1309 (2013) 76-83 DOI: http://dx.doi.org/10.1016/j.chroma.2013.08.021

5. 鈴木茂生、山本佐知雄　近畿大学薬学部生物情報薬学研究室を訪ねて. ぶんせき, 2013, 479-480

6. Yamamoto S, Kakehi K., Role of Academic Education for the Training of Experts for Bioanalysis. Chromatography, 34 (2013) 157-160

7. Suzuki S, Recent Development in Liquid Chromatography and Capillary Electrophoresis for the Analysis of Glycoprotein Glycans, Anal. Sci., 29 (2013) 1117-1128 DOI: http://dx.doi.org/10.2116/analsci.29.1117

学術論文（2012年度）

1. Tanaka Y, Okuda S, Sawai A, Suzuki S., Development of N-acetyl-β-D-glucosaminidase (NAG) Assay on a Centrifugal Lab-on-a-compact-disc (Lab-CD) Platform, Anal. Sci., 28 (2012) 33-38 DOI:http://www.jsac.or.jp/analsci/toc.php/28/1/
2. Fukushima E, Yagi Y, Yamamoto S, Nakatani Y, Kakehi K, Hayakawa T, Suzuki S., Partial filling affinity capillary electrophoresis using large-volume sample stacking with an electroosmotic flow pump for sensitive profiling of glycoprotein-derived oligosaccharides, J. Chromatogr. A, 1246 (2012) 84-89 DOI: http://dx.doi.org/10.1016/j.chroma.2012.02.052
3. Yamamoto S, Suzuki S, Suzuki S, Microchip Electrophoresis of Oligosaccharides Using Lectin-Immobilized Preconcentrator Gels Fabricated by In Situ Photopolymerization, Analyst, 137 (2012) 2211-2217 DOI: 10.1039/C2AN16015C
4. 山本佐知雄、光重合性アクリルアミドを利用したマイクロチップ電気泳動における新規オンライン濃縮電気泳動法の開発, YAKUGAKU ZASSHI, 132(9) (2012) 1031-1035
5. Yagi Y, Kakehi K, Hayakawa T, Ohyama Y, Suzuki S., Specific detection of N-glycolylneuraminic acid and Galα1-3Gal epitopes of therapeutic antibodies by partial-filling capillary electrophoresis, Anal. Biochem. 431 (2012) 120-126 DOI: http://dx.doi.org/10.1016/j.ab.2012.09.006

学術論文（2011年度）

1. Yodoshi M, Ikuta T, Mouri Y, Suzuki S., Specific Extraction of Sialic-Acid-containing Glycans and Glycopeptides Using Serotonin-bonded Silica, Anal. Sci., 27 (2011) 395-400 DOI: http://dx.doi.org/10.2116/analsci.27.395
2. Yamamoto S, Shinohara C, Fukushima E, Kakehi K, Hayakawa T, Suzuki S., Paratial filling affinity capillary affinity electrophoresis of glycoprotein oligosaccharides derivatized with 8-aminopyrene-1,3,6-trisulfonic acid, J. Chromatogr. A, 1218 (2011) 4772-4778 DOI: 10.1016/j.chroma.2011.05.057.
3. Yagi Y, Yamamoto S, Kakehi K, Hayakawa T, Ohyama T, Suzuki S., Application of partial filling capillary electrophoresis using lectins and glycosidases to the characterization of oligosaccharides in therapeutic antibody, Electrophoresis, 32 (2011) 2979-2985 DOI: 10.1002/elps.201100126
4. Yamamoto S, Watanabe Y, Nishida N, Suzuki S, Simultaneous Concentration Enrichment and Electrophoretic Separation of Weak Acids on a Microchip, Using in situ Photopolymerized Carboxylate-type Polyacrylamide Gels as the Permselective Preconcentrator, J. Sep. Sci., 34 (2011) 2879-2884 DOI: 10.1002/jssc.201100423
5. Oyama T, Yodoshi M, Yamane A, Kakehi K, Hayakawa T, Suzuki S., Rapid and Sensitive Analyses of Glycoprotein-derived Oligosaccharides by Liquid Chromatography and Laser-induced Fluorometric Detection Capillary Electrophoresis, J. Chromatogr. B, 879 (2011) 2928-2934 DOI: 10.1016/j.jchromb.2011.08.026.

学術論文（2010年度）

1. 山本佐知雄、鈴木茂生　技術講座　免疫血清　キャピラリー電気泳動と検査への応用、検査と技術、Vol 38(12) 1138-1145

学術論文（2009年度）

1. 吉年　正宏，生田　朋子，毛利　幸恵，小山　武裕，鈴木　茂生, 複合糖質のLC/MS分析のための特異的濃縮法の開発, Chormatography 30 (2009) 61-67
2. Yodoshi M, Ikuta T, Mouri Y, Suzuki S., Specific Extraction of Sialic-Acid-containing Glycans and Glycopeptides Using Serotonin-bonded Silica, Anal. Sci., 26 (2010) 75-81