Co-organized by Japanese Association for Protein Phosphatase Research ＆ MEXT-supported Program for Strategic Research Foundation at Private Universities (Rep, Reiko Sugiura)

Opening Lecture

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　・Michel Tremblay (McGill University, Canada)
"Applying protein tyrosine phosphatase inhibitors in cancer therapeutics"
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Special Seminar

　　　　　　　　　　　

　・Hideyuki Saya (Keio University, Japan)
"Cancer heterogeneity and plasticity based on cancer stem cell biology"
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Invited Speakers

　　　　　　　　　　　

　・Mathieu Bollen (University of Leuven, Belgium)
"Protein phosphatase PP1-NIPP1 limits the DNA-repair capacity"
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　・David Brautigan (University of Virginia, USA)
"Control of Lymphocytes by Protein Phosphatase-6 and SAPS1"
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　・Martha Cyert (Stanford University, USA)
"IDENTIFYING THE HUMAN CALCINEURIN SIGNALING NETWORK"
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　・Yutaka Kondo (Nagoya City University, Japan)
"Epigenetic Regulation by Notch Signaling in Glioma"
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　・Tzu-Ching Meng (Academia Sinica, Taipei)
"Structural basis for PTPN3-p38gamma complex involved in colon cancer progression"
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　・Benjamin Neel (Perlmutter Cancer Center, USA)
"A Surprising Role for PTP1B in Breast Cancer"
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　・Shirish Shenolikar (Duke University, USA)
"Multiple Roles for eIF2alpha Phosphatases in the Unfolded Stress Response"
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　・Takashi Toda (Hiroshima University, Japan)
"Roles of protein phosphatases in cell polarity control"
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　・Nicholas Tonks (Cold Spring Harbor Laboratory, USA)
"Drugging the undruggable: exploiting PTP1B as a theraieutic target"
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　・Zhenghe John Wang (Case Western Reserve University, USA)
"PTPRT is a tumor suppressor that regulates intestinal stem cell proliferation"
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Speakers

　　　　　　　　　　　

　・Ari Elson (The Weizmann Institute of Science, Israel)
"The roles of PTPROt in chronic lymphocytic leukemia"
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　・Fawaz Haj (University of California Davis, USA)
"Protein tyrosine phosphatases 1B deficiency in podocytes protects against hyperglycemia-induced renal injury"
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